Syndrome W Publications & Presentations

2008: Growth hormone treatment of adults with Prader-Willi syndrome

Growth hormone treatment of adults with Prader-Willi syndrome

Dr. Mogul authored a study called "Growth hormone treatment of adults with Prader-Willi syndrome and growth hormone deficiency improves lean body mass, fractional body fat, and serum triiodothyronine without glucose impairment: results from the United States multicenter trial."

Authors: Mogul HR, Lee PD, Whitman BY, Zipf WB, Frey M, Myers S, Cahan M, Pinyerd B, Southren AL.

Source: Department of Medicine, Division of Endocrinology, New York Medical College, 490 Munger Pavilion, Valhalla, New York 10595, USA. [email protected]

CONTEXT:
GH replacement in Prader-Willi syndrome (PWS) children has well-defined benefits and risks and is used extensively worldwide. Its use in PWS adults has been limited by documentation of benefits and risks, as determined by larger multisite studies.

OBJECTIVES:
Our objective was to evaluate the effectiveness and safety of GH in GH-deficient genotype-positive PWS adults.

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