Syndrome W Publications & Presentations
2016: METFORMIN SUSTAINED WEIGHT LOSS AND REDUCED ANDROID FAT TISSUE
Dr. Mogul has just authored Metformin Sustained Weight Loss And Reduced Android Fat Tissue At 12 Months In Empowir (Enhance The Metabolic Profile Of Women With Insulin Resistance): A Double Blind, Placebo-Controlled, Randomized Trial Of Normoglycemic Women With Midlife Weight Gain.
Authors: Harriette R. Mogul , Ruth Freeman, Khoa Nguyen
Source: Department of Medicine, Division of Endocrinology, New York Medical College, 19 Skyline Dr., Hawthorne, New York 10532, USA. [email protected]
CONTEXT: Progressive midlife weight gain is associated with multiple adverse health outcomes and may represent an early manifestation of insulin resistance in a distinct subset of women. Emerging data implicate hyperinsulinema as a proximate cause of weight gain and support strategies that attenuate insulin secretion.
Objectives: To assess 12-month body weight (BW) and body composition changes in normoglycemic women with midlife weight gain, after dietary and pharmacological interventions targeting hyperinsulinemia.